Jesse McWaters, global policy chief of Mastercard, stated that the United States has reached a "turning point" in stablecoin regulation and the adoption of digital assets, with the passage of the "Genius Act" serving as a catalyst for institutional participation, marking a "new era of clarity and confidence in digital asset regulation".

The bill allows regulated entities (including banks and businesses) to issue dollar-backed stablecoins, subject to strict reserve, disclosure, and compliance requirements. This is the first specialized legislation on cryptocurrency to become law in the United States.